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A bill that would require mandatory vaccinations for nearly all children enrolled in schools is on its way to Gov. Jerry Brown’s desk after clearing its last legislative hurdle Monday afternoon.

The measure — one of the toughest vaccination bills in the country — has sparked heated and emotional debate in the Capitol since it was introduced in February in the wake of an outbreak of measles at Disneyland that ultimately infected more than 150 people.

The state Senate, which first approved the measure in May, voted 24-14 in favor of minor amendments to the legislation, which passed the Assembly last week. Monday’s votes were cast mainly along partisan lines, with most Democrats voting in favor.

“The science remains unequivocal that vaccines are safe and vaccines save lives,” said Sen. Richard Pan (D-Sacramento), a pediatrician and an author of the bill.

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